Basic Information
ID: ALA4353451
Type: Binding
Description: Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as increase in degradation of MDM2 at 10 to 100 nM measured after 12 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Protein cereblon/E3 ubiquitin-protein ligase Mdm2(ALA4523702)
Document: ALA4350988
Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as increase in degradation of MDM2 at 10 to 100 nM measured after 12 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4353451
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 859.85 | 7.78 | 7.78 |
| 859.85 | 7.78 | 7.78 |
| 901.89 | 8.09 | 8.09 |
| 972.97 | 7.60 | 7.60 |