ID: ALA4353458
Type: Binding
Description: Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as reduction in MDM2 degradation at 100 nM preincubated with lenalidomide for 2 hrs followed by compound addition measured after 4 hrs by Western blot analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4353458
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
859.85 | 7.78 | 7.78 |