Assay Report Card

Basic Information

ID: ALA4353458

Type: Binding

Description: Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as reduction in MDM2 degradation at 100 nM preincubated with lenalidomide for 2 hrs followed by compound addition measured after 4 hrs by Western blot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
859.857.787.78