Basic Information
ID: ALA4353459
Type: Binding
Description: Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as MDM2 degradation at 100 nM preincubated with proteasome inhibitior MG132 for 2 hrs followed by compound addition measured after 4 hrs by Western blot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4353459
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 859.85 | 7.78 | 7.78 |