Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as upregulation of P21 expression at 1 uM measured after 6 hrs by qRT-PCR method

Basic Information

ID: ALA4353461

Type: Binding

Description: Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as upregulation of P21 expression at 1 uM measured after 6 hrs by qRT-PCR method

Format: BAO_0000219

Organism: Homo sapiens

Target:  Protein cereblon/E3 ubiquitin-protein ligase Mdm2(ALA4523702)

Document:  ALA4350988

Protac activity at CRBN/MDM2 in human RS4:11 cells assessed as upregulation of P21 expression at 1 uM measured after 6 hrs by qRT-PCR method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
579.577.267.26