Basic Information
ID: ALA4353598
Type: Binding
Description: Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli at 10 uM using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incubated for 3 hrs measured up to 30 mins by fluorescence assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 2(ALA4462)
Document: ALA4350992
Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli at 10 uM using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incubated for 3 hrs measured up to 30 mins by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4353598
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 332.40 | 4.15 | 4.15 |
| 390.44 | 3.87 | 3.87 |
| 382.46 | 5.30 | 5.30 |
| 404.47 | 3.95 | 3.95 |
| 346.43 | 4.08 | 4.08 |
| 402.54 | 5.97 | 5.97 |
| 408.48 | 3.63 | 3.63 |
| 560.70 | 5.20 | 5.20 |
| 402.54 | 5.83 | 5.83 |
| 403.48 | 3.66 | 3.66 |
| 376.46 | 3.77 | 3.77 |
| 370.45 | 4.41 | 4.41 |
| 574.72 | 5.59 | 5.59 |
| 422.53 | 5.98 | 5.98 |
| 402.49 | 4.52 | 4.52 |
| 374.48 | 5.19 | 5.19 |
| 436.56 | 6.02 | 6.02 |
| 505.66 | 6.45 | 6.45 |
| 408.50 | 6.30 | 6.30 |
| 388.51 | 5.53 | 5.53 |
| 475.59 | 5.31 | 5.31 |
| 489.62 | 5.70 | 5.70 |
| 557.65 | 2.68 | 2.68 |
| 389.45 | 3.27 | 3.27 |
| 362.43 | 4.34 | 4.34 |
| 388.51 | 5.58 | 5.58 |
| 414.55 | 6.11 | 6.11 |
| 333.39 | 4.75 | 4.75 |
| 432.52 | 5.24 | 5.24 |
| 348.40 | 4.17 | 4.17 |
| 403.53 | 4.34 | 4.34 |
| 407.50 | 3.67 | 3.67 |