Assay Report Card

Basic Information

ID: ALA4353689

Type: Binding

Description: Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as substrate and 2OG as cosubstrate pre-incubated for 10 mins before substrate addition followed by centrifugation for 1 min and measured after 20 mins by AlphaScreen assay

Organism: Homo sapiens

Cell type: Sf9

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
454.583.643.64
478.563.383.38
471.613.033.03
513.652.802.80
352.442.342.34
418.483.073.07
426.523.033.03
338.422.092.09
428.502.572.57
513.652.802.80
472.593.963.96
442.574.054.05
310.361.311.31
390.451.621.62
551.624.544.54
456.594.224.22
483.583.053.05
364.452.482.48
364.452.632.63
350.432.092.09
430.512.932.93
499.622.762.76
581.643.823.82
478.563.383.38
477.573.993.99
324.391.701.70
477.573.993.99
477.573.993.99
477.573.993.99
448.963.753.75
471.613.033.03
477.573.993.99
483.623.523.52