Assay Report Card

Basic Information

ID: ALA4353690

Type: Binding

Description: Inhibition of KDM5B (unknown origin) assessed as decrease in demethylation of substrate using peptide (H3(1-21)K4-Me3-GGKBiotin) as substrate and 2OG as cosubstrate pre-incubated for 15 mins before substrate addition followed by centrifugation for 15 secs and measured after 20 mins by Alphascreen assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
454.583.643.64
478.563.383.38
471.613.033.03
513.652.802.80
352.442.342.34
418.483.073.07
426.523.033.03
338.422.092.09
428.502.572.57
513.652.802.80
472.593.963.96
442.574.054.05
310.361.311.31
390.451.621.62
551.624.544.54
456.594.224.22
483.583.053.05
364.452.482.48
364.452.632.63
350.432.092.09
430.512.932.93
499.622.762.76
581.643.823.82
478.563.383.38
477.573.993.99
324.391.701.70
477.573.993.99
477.573.993.99
477.573.993.99
448.963.753.75
471.613.033.03
477.573.993.99
483.623.523.52