Basic Information
ID: ALA4354022
Type: ADME
Description: Metabolic stability in rat liver microsomes assessed as half life incubated for 20 to 60 mins in presence of metabolic phase 1 cofactors by HPLC-LC/MS analysis
Format: BAO_0000251
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4351001
Metabolic stability in rat liver microsomes assessed as half life incubated for 20 to 60 mins in presence of metabolic phase 1 cofactors by HPLC-LC/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4354022
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.50 | 4.36 | 4.36 |
| 353.45 | 2.48 | 2.48 |
| 398.38 | 4.92 | 4.92 |
| 438.51 | 3.93 | 3.93 |
| 394.46 | 3.54 | 3.54 |
| 446.48 | 4.26 | 4.26 |
| 456.50 | 4.07 | 4.07 |
| 452.54 | 4.19 | 4.19 |
| 380.43 | 3.23 | 3.23 |
| 438.94 | 4.31 | 4.31 |
| 388.88 | 3.16 | 3.16 |
| 442.47 | 3.68 | 3.68 |
| 455.34 | 3.01 | 3.01 |
| 438.51 | 3.80 | 3.80 |
| 410.46 | 3.24 | 3.24 |