Basic Information
ID: ALA4354101
Type: Binding
Description: Agonist activity at human constitutive androstane receptor expressed in HepG2 cells co-expressing CYP2B6 assessed as maximum efficacy incubated for 23 hrs by One-Glo luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Nuclear receptor subfamily 1 group I member 3(ALA5503)
Document: ALA4351005
Agonist activity at human constitutive androstane receptor expressed in HepG2 cells co-expressing CYP2B6 assessed as maximum efficacy incubated for 23 hrs by One-Glo luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4354101
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.75 | 6.57 | 6.57 |
| 420.73 | 5.89 | 5.89 |
| 416.38 | 6.01 | 6.01 |
| 446.80 | 5.81 | 5.81 |
| 354.31 | 4.60 | 4.60 |
| 437.78 | 6.78 | 6.78 |
| 434.78 | 6.68 | 6.68 |
| 383.52 | 5.55 | 5.55 |
| 402.35 | 5.70 | 5.70 |
| 379.92 | 4.97 | 4.97 |
| 450.82 | 6.70 | 6.70 |
| 458.46 | 7.00 | 7.00 |
| 427.36 | 5.57 | 5.57 |
| 367.91 | 5.05 | 5.05 |
| 436.80 | 6.36 | 6.36 |
| 353.88 | 5.01 | 5.01 |
| 452.41 | 6.86 | 6.86 |
| 450.78 | 6.00 | 6.00 |
| 379.46 | 5.00 | 5.00 |
| 402.35 | 5.70 | 5.70 |
| 431.75 | 5.69 | 5.69 |
| 389.91 | 6.48 | 6.48 |
| 450.82 | 6.66 | 6.66 |
| 402.35 | 5.70 | 5.70 |
| 436.80 | 6.36 | 6.36 |
| 395.53 | 5.47 | 5.47 |
| 420.34 | 5.84 | 5.84 |
| 406.94 | 5.53 | 5.53 |
| 385.90 | 5.19 | 5.19 |
| 432.38 | 5.71 | 5.71 |
| 470.35 | 6.72 | 6.72 |
| 481.25 | 6.46 | 6.46 |
| 383.90 | 4.75 | 4.75 |