Basic Information
ID: ALA4354316
Type: Binding
Description: Agonist activity at alpha7 nAChR in human SH-SY5Y cells assessed as release of intracellular calcium at 3 nM preincubated for 20 mins with alpha7 nAChR antagonist alpha-bungarotoxin and for 1 min with alpha7 nAChR PAM PNU120596 prior to compound addition by Fluo-3 AM staining-based fluorescence spectral scanning multimode reader analysis
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA4354316
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.63 | 4.93 | 4.93 |