Basic Information
ID: ALA4354322
Type: Binding
Description: Agonist activity at alpha7 nAChR in human SH-SY5Y cells assessed as release of intracellular calcium at 50 nM preincubated for 20 mins with alpha7 nAChR antagonist alpha-bungarotoxin and for 1 min with alpha7 nAChR PAM PNU120596 prior to compound addition by Fluo-3 AM staining-based fluorescence spectral scanning multimode reader analysis
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA4354322
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.48 | 4.41 | 4.41 |