Basic Information
ID: ALA4354362
Type: Binding
Description: Inhibition of recombinant human His-tagged TrkA catalytic domain (441 to 796 residues) expressed in baculovirus expression system using tyr 01 as substrate incubated for 1 hr by Z'-Lyte assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4354362
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.44 | 2.95 | 2.95 |
| 532.57 | 4.46 | 4.46 |
| 548.57 | 4.16 | 4.16 |
| 631.78 | 6.35 | 6.35 |
| 532.57 | 4.46 | 4.46 |
| 569.71 | 4.99 | 4.99 |
| 597.77 | 5.81 | 5.81 |
| 609.66 | 5.52 | 5.52 |
| 623.68 | 5.71 | 5.71 |
| 560.62 | 5.10 | 5.10 |
| 560.62 | 5.27 | 5.27 |
| 532.57 | 4.46 | 4.46 |
| 532.57 | 4.46 | 4.46 |
| 608.67 | 6.12 | 6.12 |
| 546.60 | 4.71 | 4.71 |
| 552.99 | 4.80 | 4.80 |
| 611.79 | 5.98 | 5.98 |
| 583.74 | 5.25 | 5.25 |
| 518.54 | 4.15 | 4.15 |