Basic Information
ID: ALA4354676
Type: ADME
Description: Inhibition of recombinant human CYP3A4 using Luciferin-PPXE as substrate preincubated for 10 mins followed by NADPH addition measured after 15 mins by luminometric method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4354676
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 344.85 | 5.38 | 5.38 |
| 306.28 | 0.74 | 0.74 |
| 349.32 | 2.18 | 2.18 |
| 531.44 | 4.21 | 4.21 |
| 700.79 | 4.57 | 4.57 |
| 497.50 | 2.83 | 2.83 |
| 530.41 | 3.86 | 3.86 |
| 545.42 | 4.58 | 4.58 |
| 529.42 | 4.46 | 4.46 |
| 512.51 | 3.55 | 3.55 |
| 511.53 | 4.15 | 4.15 |
| 496.51 | 3.43 | 3.43 |
| 544.44 | 5.18 | 5.18 |