Basic Information
ID: ALA4354689
Type: Binding
Description: Inhibition of wild type RyR3 (unknown origin) stably expressed in HEK293 cells coexpressing R-CEPIA1er assessed as suppression in caffeine-activated Ca2+ leakage from ER at 10 uM compound addition at 100 secs and measured every 10 secs for 300 secs by fluorometric analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Ryanodine receptor 3(ALA2062)
Document: ALA4351027
Inhibition of wild type RyR3 (unknown origin) stably expressed in HEK293 cells coexpressing R-CEPIA1er assessed as suppression in caffeine-activated Ca2+ leakage from ER at 10 uM compound addition at 100 secs and measured every 10 secs for 300 secs by fluorometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4354689
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 261.23 | 1.45 | 1.45 |
| 345.40 | 3.79 | 3.79 |
| 331.41 | 4.07 | 4.07 |
| 315.41 | 4.37 | 4.37 |