Basic Information
ID: ALA4354698
Type: Binding
Description: Reversal of ABCG2 482-G2 mutant (unknown origin) expressed in HEK293 cells-mediated multidrug resistance assessed as potentiation of mitoxantrone-induced cytotoxicity at 2.5 to 5 uM pretreated for 2 hrs followed by mitoxantrone addition and measured after 44 hrs by MTT assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4354698
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 281.31 | 3.42 | 3.42 |