Assay Report Card

Basic Information

ID: ALA4354703

Type: Binding

Description: Reversal of ABCG2-mediated multidrug resistance in human NCI-H460/MX20 cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 2.5 to 5 uM pretreated with compound for 2 hrs followed by mitoxantrone challenge for 44 hrs by MTT assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
281.313.423.42