Basic Information
ID: ALA4354725
Type: Binding
Description: Inhibition of ABCG2-mediated mitoxantrone efflux in human NCI-H460/MX20 cells assessed as increase in accumulation of [3H]MX at 5 uM incubated for 2 hrs followed by [3H]MX addition further incubated for 2 hrs by liquid scintillation counter relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4354725
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.58 | 3.64 | 3.64 |
| 281.31 | 3.42 | 3.42 |