Basic Information
ID: ALA4355543
Type: Binding
Description: Inhibition of recombinant human B-RAF V600E mutant using Ser/Thr3 as substrate after 1 hr by FRET-based Z'-Lyte assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase B-raf(ALA5145)
Document: ALA4354801
Inhibition of recombinant human B-RAF V600E mutant using Ser/Thr3 as substrate after 1 hr by FRET-based Z'-Lyte assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4355543
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.88 | 4.10 | 4.10 |
| 495.88 | 4.33 | 4.33 |
| 483.46 | 3.29 | 3.29 |
| 533.52 | 4.45 | 4.45 |
| 525.54 | 4.42 | 4.42 |
| 559.56 | 4.96 | 4.96 |
| 518.89 | 4.42 | 4.42 |
| 497.49 | 3.60 | 3.60 |
| 462.87 | 3.64 | 3.64 |
| 499.92 | 3.81 | 3.81 |
| 516.92 | 4.76 | 4.76 |
| 533.52 | 4.45 | 4.45 |
| 518.89 | 4.42 | 4.42 |
| 481.93 | 3.67 | 3.67 |
| 481.85 | 4.40 | 4.40 |
| 517.91 | 3.95 | 3.95 |
| 513.49 | 3.30 | 3.30 |
| 496.87 | 4.79 | 4.79 |
| 562.36 | 4.06 | 4.06 |
| 463.86 | 3.04 | 3.04 |
| 499.92 | 3.81 | 3.81 |
| 508.47 | 3.16 | 3.16 |
| 550.82 | 4.98 | 4.98 |