Basic Information
ID: ALA4355837
Type: Binding
Description: Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta5 (24 to 719 residues) expressed in CHO cells preincubated for 15 mins followed by Cy3B-RGD probe addition and measured after 2 hrs by fluorescence polarization assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4355837
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.94 | 4.74 | 4.74 |
| 453.93 | 4.13 | 4.13 |
| 453.93 | 4.13 | 4.13 |
| 517.63 | 3.92 | 3.92 |
| 510.59 | 5.88 | 5.88 |
| 517.63 | 3.92 | 3.92 |
| 498.63 | 5.84 | 5.84 |
| 452.94 | 4.74 | 4.74 |
| 435.50 | 4.83 | 4.83 |
| 497.39 | 4.85 | 4.85 |
| 453.93 | 4.13 | 4.13 |
| 453.93 | 4.13 | 4.13 |
| 453.93 | 4.13 | 4.13 |
| 453.93 | 4.13 | 4.13 |
| 453.93 | 4.13 | 4.13 |
| 486.49 | 5.10 | 5.10 |
| 452.94 | 4.74 | 4.74 |
| 453.93 | 4.13 | 4.13 |
| 453.93 | 4.13 | 4.13 |
| 436.49 | 4.22 | 4.22 |
| 458.56 | 4.96 | 4.96 |
| 416.52 | 4.86 | 4.86 |
| 452.94 | 4.74 | 4.74 |
| 453.93 | 4.13 | 4.13 |