Basic Information
ID: ALA4356124
Type: Binding
Description: Inhibition of C-terminal His6-tagged human IDO2 (14 to 420 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in conversion of L-tryptophan to N-formyl kynurenine using L-tryptophan as substrate after 30 mins by methylene blue dye based microplate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4356124
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.24 | 0.42 | 0.42 |
| 364.38 | 1.47 | 1.47 |
| 378.41 | 1.82 | 1.82 |
| 323.33 | 2.13 | 2.13 |
| 309.30 | 2.14 | 2.14 |
| 350.35 | 1.48 | 1.48 |
| 346.39 | 1.68 | 1.68 |
| 364.38 | 1.82 | 1.82 |
| 360.42 | 1.68 | 1.68 |
| 464.50 | 3.12 | 3.12 |
| 349.37 | 3.06 | 3.06 |
| 333.35 | 1.77 | 1.77 |
| 365.36 | 1.90 | 1.90 |