Basic Information
ID: ALA4356149
Type: Functional
Description: In vivo inhibition of IDO1/2/TDO in C57BL/6 mouse assessed as decrease in LPS-stimulated kynurenine pathway by measuring increase in serum tryptophan level at 60 mg/kg, ig pretreated for 24 hrs with Escherichia coli LPS followed by compound treatment measured at 12 hrs post-treatment by HPLC analysis
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4356149
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.41 | 1.82 | 1.82 |