Assay Report Card

Basic Information

ID: ALA4356151

Type: Functional

Description: In vivo inhibition of IDO1/2/TDO in C57BL/6 mouse assessed as decrease in LPS-stimulated kynurenine pathway by measuring decrease in ratio of kynurenine to tryptophan level in serum at 60 mg/kg, ig pretreated for 24 hrs with Escherichia coli LPS followed by compound treatment measured at 24 hrs post-treatment by HPLC analysis

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
378.411.821.82