Assay Report Card

Basic Information

ID: ALA4356302

Type: Toxicity

Description: Hepatotoxicity in Swiss mouse model of amyloid-beta (25 to 35)-induced Alzheimer disease assessed as necrosis incidence level at 3 mg/kg, ip administered 20 mins after amyloid-beta (25 to 35) stimulation for 7 days and observed on day 11 by hematoxylin-eosin staining based assay (Rvb = 91%)

Organism: Mus musculus

Strain: Swiss

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
681.978.728.72
575.767.057.05
617.848.228.22
589.787.347.34