Basic Information
ID: ALA4356424
Type: Binding
Description: Inhibition of human TLR8 expressed in HEK293 cells assessed as reduction in R848-induced NFkappaB production incubated for 16 hrs by quanti-blue SEAP assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4356424
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.77 | 6.54 | 6.54 |
| 463.78 | 7.92 | 7.92 |
| 311.73 | 3.84 | 3.84 |
| 535.66 | 7.15 | 7.15 |
| 287.71 | 3.76 | 3.76 |
| 477.76 | 7.56 | 7.56 |
| 410.75 | 5.94 | 5.94 |
| 569.21 | 7.51 | 7.51 |
| 569.21 | 7.51 | 7.51 |
| 488.66 | 7.31 | 7.31 |
| 385.67 | 5.77 | 5.77 |
| 527.31 | 7.81 | 7.81 |
| 458.33 | 6.49 | 6.49 |
| 317.69 | 4.09 | 4.09 |
| 459.32 | 6.61 | 6.61 |
| 491.79 | 7.59 | 7.59 |
| 427.76 | 6.68 | 6.68 |
| 459.32 | 6.61 | 6.61 |
| 465.35 | 6.65 | 6.65 |
| 477.76 | 7.56 | 7.56 |
| 585.21 | 7.22 | 7.22 |
| 458.33 | 6.49 | 6.49 |
| 444.21 | 7.20 | 7.20 |
| 477.76 | 7.56 | 7.56 |
| 465.80 | 7.48 | 7.48 |
| 409.14 | 4.04 | 4.04 |
| 493.76 | 7.27 | 7.27 |
| 511.31 | 7.93 | 7.93 |
| 522.21 | 7.67 | 7.67 |
| 297.70 | 4.05 | 4.05 |
| 238.25 | 3.53 | 3.53 |
| 443.32 | 6.91 | 6.91 |
| 464.37 | 7.25 | 7.25 |
| 569.21 | 7.51 | 7.51 |
| 342.15 | 4.16 | 4.16 |