Basic Information
ID: ALA4356434
Type: Binding
Description: Inhibition of human TLR8 expressed in HEK293 cells assessed as reduction in R848-induced NFkappaB production at 1.5 to 5 uM incubated for 16 hrs by quanti-blue SEAP assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4356434
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 461.31 | 7.05 | 7.05 |
| 566.21 | 7.80 | 7.80 |
| 339.74 | 3.79 | 3.79 |
| 296.71 | 4.66 | 4.66 |
| 431.38 | 7.04 | 7.04 |
| 444.31 | 6.30 | 6.30 |
| 479.37 | 6.46 | 6.46 |
| 467.34 | 6.89 | 6.89 |
| 297.70 | 4.05 | 4.05 |
| 515.28 | 7.46 | 7.46 |
| 513.82 | 7.11 | 7.11 |
| 425.76 | 6.25 | 6.25 |
| 477.76 | 7.56 | 7.56 |
| 415.29 | 6.36 | 6.36 |