Basic Information
ID: ALA4356477
Type: Binding
Description: Inhibition of P-gp overexpressed in human DU145-TxR cells assessed as increase in cellular accumulation of calcein AM at 2 uM preincubated for 6 hrs followed by calcein AM addition by fluorescence imaging analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4356477
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 519.63 | 6.01 | 6.01 |
| 516.64 | 5.59 | 5.59 |
| 626.58 | 7.61 | 7.61 |
| 534.69 | 6.93 | 6.93 |
| 458.59 | 5.19 | 5.19 |
| 557.72 | 7.59 | 7.59 |
| 541.70 | 6.38 | 6.38 |
| 542.75 | 6.22 | 6.22 |
| 574.75 | 7.04 | 7.04 |
| 586.76 | 7.60 | 7.60 |
| 574.70 | 5.80 | 5.80 |