Basic Information
ID: ALA4356486
Type: Binding
Description: Ratio of inhibition of P-gp overexpressed in human DU145-TxR cells assessed as increase in intracellular compound accumulation after 2.5 hrs in presence of tariquidar by LC-MS/MS analysis to Inhibition of P-gp overexpressed in human DU145-TxR cells assessed as decrease in intracellular compound accumulation after 2.5 hrs in absence of tariquidar by LC-MS/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4356486
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 519.63 | 6.01 | 6.01 |
| 516.64 | 5.59 | 5.59 |
| 626.58 | 7.61 | 7.61 |
| 534.69 | 6.93 | 6.93 |
| 458.59 | 5.19 | 5.19 |
| 557.72 | 7.59 | 7.59 |
| 541.70 | 6.38 | 6.38 |
| 542.75 | 6.22 | 6.22 |
| 574.75 | 7.04 | 7.04 |
| 586.76 | 7.60 | 7.60 |
| 574.70 | 5.80 | 5.80 |