Basic Information
ID: ALA4356586
Type: Binding
Description: Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incubated for 60 mins in presence of 0.05 nM biotin-Bim by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4356586
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 609.16 | 4.67 | 4.67 |
| 802.41 | 3.80 | 3.80 |
| 820.40 | 4.09 | 4.09 |
| 613.22 | 5.90 | 5.90 |
| 636.23 | 4.94 | 4.94 |
| 581.11 | 3.89 | 3.89 |
| 623.19 | 5.02 | 5.02 |
| 848.45 | 4.87 | 4.87 |
| 597.15 | 4.50 | 4.50 |
| 608.18 | 4.34 | 4.34 |
| 838.42 | 3.36 | 3.36 |
| 609.16 | 4.93 | 4.93 |
| 411.93 | 5.31 | 5.31 |
| 489.04 | 4.30 | 4.30 |
| 715.31 | 3.77 | 3.77 |
| 786.39 | 3.23 | 3.23 |
| 814.45 | 3.47 | 3.47 |
| 595.14 | 4.28 | 4.28 |
| 595.18 | 4.84 | 4.84 |
| 441.95 | 4.73 | 4.73 |
| 809.37 | 4.42 | 4.42 |
| 814.45 | 3.48 | 3.48 |
| 539.07 | 4.67 | 4.67 |
| 717.33 | 4.00 | 4.00 |
| 425.96 | 5.24 | 5.24 |
| 609.16 | 4.93 | 4.93 |
| 862.51 | 2.87 | 2.87 |
| 834.43 | 4.48 | 4.48 |
| 686.27 | 3.93 | 3.93 |