Assay Report Card

Basic Information

ID: ALA4356627

Type: Functional

Description: In vivo inhibition of Mcl-1 in athymic nude mouse xenografted with human OPM2 cells expressing Firefly luciferase assessed as Bax activation at 60 mg/kg, po administered as single dose on day 23 post-xenograft and measured at 6 hrs post-treatment by electrochemiluminescent immunoassay relative to control

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
820.404.094.09
613.225.905.90