Basic Information
ID: ALA4356627
Type: Functional
Description: In vivo inhibition of Mcl-1 in athymic nude mouse xenografted with human OPM2 cells expressing Firefly luciferase assessed as Bax activation at 60 mg/kg, po administered as single dose on day 23 post-xenograft and measured at 6 hrs post-treatment by electrochemiluminescent immunoassay relative to control
Format: BAO_0000218
Organism: Mus musculus
Target: Mus musculus(ALA375)
Document: ALA4354823
In vivo inhibition of Mcl-1 in athymic nude mouse xenografted with human OPM2 cells expressing Firefly luciferase assessed as Bax activation at 60 mg/kg, po administered as single dose on day 23 post-xenograft and measured at 6 hrs post-treatment by electrochemiluminescent immunoassay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4356627
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 820.40 | 4.09 | 4.09 |
| 613.22 | 5.90 | 5.90 |