Basic Information
ID: ALA4356634
Type: ADME
Description: Ratio of free drug concentration in plasma of athymic nude mouse xenografted with human OPM2 cells expressing Firefly luciferase at 60 mg/kg, po administered as single dose on day 23 post-xenograft and measured at 6 hrs post-treatment to IC50 for antiproliferative activity against human OPM2 cells assessed as reduction in cell viability after 16 hrs by CellTiter-Glo assay
Activity Charts
Bioactivity
Activity Types for Assay ALA4356634
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 820.40 | 4.09 | 4.09 |
| 613.22 | 5.90 | 5.90 |