Basic Information
ID: ALA4356794
Type: Binding
Description: Positive allosteric modulatory activity against alpha7 nAChR in human IMR-32 cells assessed as potentiation of PNU-282987-induced Ca2+ efflux at 1 uM by FLIPR assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: IMR-32
Target: Neuronal acetylcholine receptor protein alpha-7 subunit(ALA2492)
Document: ALA4354827
Positive allosteric modulatory activity against alpha7 nAChR in human IMR-32 cells assessed as potentiation of PNU-282987-induced Ca2+ efflux at 1 uM by FLIPR assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4356794
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.50 | 4.03 | 4.03 |
| 419.96 | 5.28 | 5.28 |
| 493.05 | 4.54 | 4.54 |
| 434.97 | 4.39 | 4.39 |
| 419.96 | 5.28 | 5.28 |
| 441.62 | 5.93 | 5.93 |
| 475.04 | 5.32 | 5.32 |
| 385.51 | 4.63 | 4.63 |
| 375.47 | 4.22 | 4.22 |
| 419.96 | 5.28 | 5.28 |
| 403.50 | 4.77 | 4.77 |
| 429.56 | 5.03 | 5.03 |
| 405.93 | 4.89 | 4.89 |
| 425.58 | 5.51 | 5.51 |
| 454.40 | 5.94 | 5.94 |
| 428.58 | 4.70 | 4.70 |
| 415.54 | 4.64 | 4.64 |
| 453.51 | 5.65 | 5.65 |