Basic Information
ID: ALA4357261
Type: Functional
Description: Antiproliferative activity against human A549 cells harboring KRAS G12S point mutant assessed as cell growth inhibition after 72 hrs by Celltiter-Glo luminescent cell viability assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: A549(ALA392)
Document: ALA4354832
Antiproliferative activity against human A549 cells harboring KRAS G12S point mutant assessed as cell growth inhibition after 72 hrs by Celltiter-Glo luminescent cell viability assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4357261
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 595.07 | 7.07 | 7.07 |
| 548.02 | 4.90 | 4.90 |
| 561.59 | 3.88 | 3.88 |
| 561.06 | 5.90 | 5.90 |
| 544.06 | 5.15 | 5.15 |
| 546.05 | 5.59 | 5.59 |
| 562.05 | 5.29 | 5.29 |
| 576.07 | 5.60 | 5.60 |
| 559.62 | 5.09 | 5.09 |
| 561.51 | 6.71 | 6.71 |
| 567.09 | 5.85 | 5.85 |
| 560.61 | 4.48 | 4.48 |
| 545.06 | 6.19 | 6.19 |
| 531.03 | 5.80 | 5.80 |
| 547.03 | 5.51 | 5.51 |
| 578.05 | 4.39 | 4.39 |
| 560.61 | 4.48 | 4.48 |
| 577.06 | 5.00 | 5.00 |
| 579.10 | 6.52 | 6.52 |
| 577.06 | 5.00 | 5.00 |
| 562.50 | 6.10 | 6.10 |