Basic Information
ID: ALA4357495
Type: Binding
Description: Inhibition of recombinant His6/GST-tagged human HDAC3 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence based assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Histone deacetylase 3(ALA1829)
Document: ALA4354838
Inhibition of recombinant His6/GST-tagged human HDAC3 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC as substrate after 24 hrs by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4357495
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.43 | 3.33 | 3.33 |
| 366.47 | 2.55 | 2.55 |
| 402.50 | 3.84 | 3.84 |
| 400.49 | 3.19 | 3.19 |
| 428.54 | 4.06 | 4.06 |
| 508.60 | 5.56 | 5.56 |
| 520.64 | 5.43 | 5.43 |
| 490.61 | 5.42 | 5.42 |
| 414.51 | 3.75 | 3.75 |
| 426.52 | 3.68 | 3.68 |
| 414.51 | 3.75 | 3.75 |
| 428.54 | 4.24 | 4.24 |
| 442.57 | 4.39 | 4.39 |
| 428.54 | 3.93 | 3.93 |
| 414.51 | 3.75 | 3.75 |
| 428.54 | 4.06 | 4.06 |
| 468.60 | 4.63 | 4.63 |