Assay Report Card

Basic Information

ID: ALA4357641

Type: Functional

Description: In vivo inhibition of SphK2 in C57BL/6 mouse assessed as Cmax required for two-fold increase in sphingosine-1-phosphate level in blood at 10 mg/kg, ip administered as single dose measured after 4 hrs by LC-MS/MS analysis

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
535.885.385.38