Basic Information
ID: ALA4358400
Type: Functional
Description: Cytotoxicity against human HCT116 cells harboring PIK3CA mutant assessed as reduction in cell viability measured after 72 hrs by CCK8 assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: HCT-116(ALA394)
Document: ALA4354853
Cytotoxicity against human HCT116 cells harboring PIK3CA mutant assessed as reduction in cell viability measured after 72 hrs by CCK8 assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4358400
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.47 | 3.37 | 3.37 |
| 480.53 | 0.66 | 0.66 |
| 572.59 | 2.55 | 2.55 |
| 498.47 | 3.84 | 3.84 |
| 627.10 | 3.84 | 3.84 |
| 610.65 | 3.32 | 3.32 |
| 666.71 | 2.25 | 2.25 |
| 659.63 | 3.09 | 3.09 |
| 574.57 | 5.51 | 5.51 |
| 651.70 | 3.49 | 3.49 |
| 619.66 | 2.95 | 2.95 |
| 596.62 | 3.07 | 3.07 |
| 609.66 | 2.99 | 2.99 |
| 674.65 | 3.78 | 3.78 |
| 597.60 | 3.41 | 3.41 |
| 544.64 | 3.04 | 3.04 |
| 653.67 | 2.34 | 2.34 |
| 637.67 | 3.10 | 3.10 |
| 574.67 | 3.05 | 3.05 |
| 580.62 | 3.32 | 3.32 |
| 542.52 | 3.72 | 3.72 |
| 618.58 | 4.99 | 4.99 |
| 604.55 | 4.90 | 4.90 |
| 628.54 | 6.22 | 6.22 |
| 611.63 | 2.57 | 2.57 |
| 646.64 | 4.00 | 4.00 |
| 555.57 | 3.64 | 3.64 |
| 595.63 | 4.56 | 4.56 |
| 434.50 | 1.83 | 1.83 |
| 554.58 | 3.30 | 3.30 |
| 592.66 | 3.18 | 3.18 |
| 632.61 | 3.70 | 3.70 |
| 610.65 | 3.46 | 3.46 |
| 512.60 | 1.62 | 1.62 |
| 610.65 | 3.32 | 3.32 |
| 642.66 | 4.06 | 4.06 |
| 610.65 | 3.32 | 3.32 |
| 581.60 | 4.17 | 4.17 |
| 615.07 | 3.97 | 3.97 |
| 566.57 | 5.26 | 5.26 |
| 512.50 | 4.10 | 4.10 |