Basic Information
ID: ALA4358451
Type: Binding
Description: Inhibition of IDO1 in IFN-gamma/LPS stimulated human PBMC assessed as reduction in kynurenine production after 48 hrs by RapidFire MS assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Indoleamine 2,3-dioxygenase(ALA4685)
Document: ALA4354854
Inhibition of IDO1 in IFN-gamma/LPS stimulated human PBMC assessed as reduction in kynurenine production after 48 hrs by RapidFire MS assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4358451
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 503.39 | 4.70 | 4.70 |
| 514.38 | 4.84 | 4.84 |
| 544.40 | 4.02 | 4.02 |
| 489.37 | 4.40 | 4.40 |
| 513.39 | 4.57 | 4.57 |
| 542.39 | 3.83 | 3.83 |
| 527.42 | 4.96 | 4.96 |
| 512.40 | 5.18 | 5.18 |
| 465.51 | 3.21 | 3.21 |
| 514.38 | 3.97 | 3.97 |
| 434.50 | 3.81 | 3.81 |
| 433.51 | 4.41 | 4.41 |
| 514.38 | 3.97 | 3.97 |
| 459.51 | 3.68 | 3.68 |
| 434.50 | 3.81 | 3.81 |
| 584.39 | 5.19 | 5.19 |
| 461.56 | 5.19 | 5.19 |
| 462.55 | 4.37 | 4.37 |
| 513.39 | 4.57 | 4.57 |
| 527.42 | 4.96 | 4.96 |
| 464.52 | 3.82 | 3.82 |
| 528.40 | 4.19 | 4.19 |
| 529.39 | 3.86 | 3.86 |
| 499.37 | 4.18 | 4.18 |
| 517.38 | 4.42 | 4.42 |
| 492.53 | 3.59 | 3.59 |
| 513.39 | 4.57 | 4.57 |
| 434.50 | 3.81 | 3.81 |
| 478.51 | 3.51 | 3.51 |
| 541.45 | 5.35 | 5.35 |