Basic Information
ID: ALA4358912
Type: Binding
Description: Inhibition of Trypanosoma cruzi cruzain assessed as rate constant for enzyme-inhibitor complex using Cbz-Phe-Arg-AMC as substrate and measured up to 40 mins by fluorescence assay
Format: BAO_0000357
Organism: Trypanosoma cruzi
Target: Cruzipain(ALA3563)
Document: ALA4354862
Inhibition of Trypanosoma cruzi cruzain assessed as rate constant for enzyme-inhibitor complex using Cbz-Phe-Arg-AMC as substrate and measured up to 40 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4358912
Ki(app)
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 519.65 | 5.75 | 5.75 |
| 471.56 | 3.29 | 3.29 |
| 506.61 | 4.76 | 4.76 |
| 647.56 | 4.79 | 4.79 |
| 512.66 | 3.18 | 3.18 |
| 647.56 | 4.79 | 4.79 |
| 505.62 | 5.36 | 5.36 |
| 653.59 | 4.85 | 4.85 |
| 511.67 | 3.78 | 3.78 |
| 485.58 | 3.68 | 3.68 |
| 504.63 | 5.97 | 5.97 |
| 568.70 | 5.24 | 5.24 |
| 534.68 | 5.18 | 5.18 |
| 486.62 | 4.25 | 4.25 |
| 520.63 | 5.15 | 5.15 |
| 485.63 | 5.55 | 5.55 |
| 549.67 | 5.76 | 5.76 |
| 505.62 | 5.36 | 5.36 |
| 511.65 | 5.42 | 5.42 |
| 477.61 | 1.71 | 1.71 |
| 430.51 | 3.53 | 3.53 |
| 506.61 | 4.76 | 4.76 |
| 429.52 | 4.14 | 4.14 |
| 495.58 | 4.95 | 4.95 |
| 549.63 | 5.87 | 5.87 |