Basic Information
ID: ALA4359030
Type: Binding
Description: Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level at 1 uM measured after 48 hrs by HPLC analysis relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Indoleamine 2,3-dioxygenase(ALA4685)
Document: ALA4354865
Inhibition of IDO1 in IFNgamma-stimulated human A375 cells assessed as reduction in L-Kyn level at 1 uM measured after 48 hrs by HPLC analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4359030
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 438.24 | 0.42 | 0.42 |
| 378.48 | 2.42 | 2.42 |
| 396.45 | 4.20 | 4.20 |
| 398.47 | 3.13 | 3.13 |
| 394.48 | 4.80 | 4.80 |
| 384.41 | 4.03 | 4.03 |
| 399.45 | 3.67 | 3.67 |
| 380.45 | 4.50 | 4.50 |
| 375.86 | 4.67 | 4.67 |
| 380.45 | 4.19 | 4.19 |
| 359.40 | 4.15 | 4.15 |
| 366.42 | 3.89 | 3.89 |
| 409.41 | 5.03 | 5.03 |
| 420.31 | 4.78 | 4.78 |
| 381.44 | 3.89 | 3.89 |
| 384.41 | 4.03 | 4.03 |
| 408.30 | 4.71 | 4.71 |
| 410.27 | 4.53 | 4.53 |
| 397.50 | 5.23 | 5.23 |
| 355.44 | 4.32 | 4.32 |
| 322.41 | 2.44 | 2.44 |
| 336.40 | 1.84 | 1.84 |
| 330.39 | 3.34 | 3.34 |
| 347.44 | 4.08 | 4.08 |
| 341.41 | 4.01 | 4.01 |
| 409.29 | 4.11 | 4.11 |
| 331.38 | 3.61 | 3.61 |
| 488.18 | 4.87 | 4.87 |
| 381.44 | 4.76 | 4.76 |