Basic Information
ID: ALA4359549
Type: Functional
Description: In vivo inhibition of HRAS G12V mutant transfected in mouse NIH/3T3 cells implanted BALB/c nu/nu mouse assessed as reduction in MAPK phosphorylation in tumor at 1 mg/kg, po administered once daily via gavage for 3 days measured 3 hrs post-last dose by Western blot analysis
Organism: Mus musculus
Strain: BALB/c
Activity Charts
Bioactivity
Activity Types for Assay ALA4359549
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 528.63 | 5.56 | 5.56 |