Basic Information
ID: ALA4359660
Type: Binding
Description: Binding affinity to wild type human C-terminal thrombin cleavage site-fused/ 6xHis-tagged JAK2 JH2 pseudokinase domain (536 to 812 residues) expressed in baculovirus infected sf9 insect cells measured for 1 hr in presence of fluorescein conjugate tracer by competitive fluorescence polarization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA4354882
Binding affinity to wild type human C-terminal thrombin cleavage site-fused/ 6xHis-tagged JAK2 JH2 pseudokinase domain (536 to 812 residues) expressed in baculovirus infected sf9 insect cells measured for 1 hr in presence of fluorescein conjugate tracer by competitive fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4359660
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 380.38 | 1.58 | 1.58 |
| 394.36 | 1.22 | 1.22 |
| 391.42 | 3.42 | 3.42 |
| 393.36 | 2.02 | 2.02 |
| 483.47 | 2.29 | 2.29 |
| 484.45 | 1.68 | 1.68 |
| 374.39 | 0.73 | 0.73 |
| 374.39 | 0.73 | 0.73 |
| 373.40 | 1.33 | 1.33 |
| 447.43 | 0.79 | 0.79 |
| 461.46 | 0.88 | 0.88 |
| 443.45 | 1.43 | 1.43 |
| 393.36 | 2.02 | 2.02 |
| 485.44 | 1.08 | 1.08 |
| 387.43 | 1.36 | 1.36 |