Basic Information
ID: ALA4359661
Type: Binding
Description: Binding affinity to human C-terminal thrombin cleavage site-fused/ 6xHis-tagged JAK2 JH2 pseudokinase domain V617F mutant (536 to 812 residues) expressed in baculovirus infected sf9 insect cells measured for 1 hr in presence of fluorescein conjugate tracer by competitive fluorescence polarization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA4354882
Binding affinity to human C-terminal thrombin cleavage site-fused/ 6xHis-tagged JAK2 JH2 pseudokinase domain V617F mutant (536 to 812 residues) expressed in baculovirus infected sf9 insect cells measured for 1 hr in presence of fluorescein conjugate tracer by competitive fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4359661
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.36 | 1.22 | 1.22 |
| 484.45 | 1.68 | 1.68 |
| 447.43 | 0.79 | 0.79 |
| 443.45 | 1.43 | 1.43 |