Basic Information
ID: ALA4359662
Type: ADME
Description: Binding affinity to wild type human N-terminal TEV cleavage site-fused/His6-tagged JAK2 JH1 domain (840 to 1132 residues) expressed in baculovirus infected sf9 insect cells measured for1 hr in presence of fluorescein conjugate tracer by competitive fluorescence polarization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA4354882
Binding affinity to wild type human N-terminal TEV cleavage site-fused/His6-tagged JAK2 JH1 domain (840 to 1132 residues) expressed in baculovirus infected sf9 insect cells measured for1 hr in presence of fluorescein conjugate tracer by competitive fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4359662
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.36 | 1.22 | 1.22 |
| 484.45 | 1.68 | 1.68 |
| 447.43 | 0.79 | 0.79 |
| 443.45 | 1.43 | 1.43 |