Basic Information
ID: ALA4359667
Type: Binding
Description: Inhibition of full length human C-terminal FLAG-tagged JAK2 V617F mutant (1 to 1132 residues) autophosphorylation expressed in HEK293T cells incubated in buffer with compound for 1 hr followed by treatment with enzyme and [gamma32P]-ATP for 15 mins by immunoprecipitation assay based autoradiography
Format: BAO_0000219
Organism: Homo sapiens
Target: Tyrosine-protein kinase JAK2(ALA2971)
Document: ALA4354882
Inhibition of full length human C-terminal FLAG-tagged JAK2 V617F mutant (1 to 1132 residues) autophosphorylation expressed in HEK293T cells incubated in buffer with compound for 1 hr followed by treatment with enzyme and [gamma32P]-ATP for 15 mins by immunoprecipitation assay based autoradiography: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4359667
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.36 | 1.22 | 1.22 |
| 447.43 | 0.79 | 0.79 |