Basic Information
ID: ALA4359946
Type: ADME
Description: Apparent permeability from apical to basolateral side in MDCK cells at 10 uM incubated for 180 mins and measured up to 180 min by LC-MS/MS analysis
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK
Target: ADMET(ALA612558)
Document: ALA4359811
Apparent permeability from apical to basolateral side in MDCK cells at 10 uM incubated for 180 mins and measured up to 180 min by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4359946
Papp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.54 | 1.56 | 1.56 |
| 409.45 | 1.50 | 1.50 |
| 418.46 | 2.40 | 2.40 |
| 409.45 | 2.24 | 2.24 |
| 409.45 | 1.50 | 1.50 |
| 421.50 | 2.90 | 2.90 |
| 393.45 | 2.53 | 2.53 |
| 493.59 | 2.64 | 2.64 |
| 459.45 | 3.13 | 3.13 |
| 490.57 | 1.91 | 1.91 |
| 449.52 | 1.30 | 1.30 |
| 423.47 | 2.02 | 2.02 |
| 436.47 | 1.63 | 1.63 |
| 448.53 | 2.22 | 2.22 |
| 465.54 | 2.26 | 2.26 |
| 437.50 | 2.28 | 2.28 |
| 436.52 | 1.81 | 1.81 |