Basic Information
ID: ALA4360137
Type: Binding
Description: Inhibition of recombinant human ICMT expressed in Sf9 insect cell membranes at 50 uM using biotin-farnesyl-L-cysteine as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by scintillation counting analysis relative to control
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4360137
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.60 | 5.71 | 5.71 |
| 473.68 | 5.14 | 5.14 |
| 435.70 | 5.33 | 5.33 |
| 389.58 | 4.59 | 4.59 |
| 495.71 | 4.53 | 4.53 |
| 441.59 | 5.85 | 5.85 |
| 429.65 | 5.52 | 5.52 |
| 448.61 | 5.58 | 5.58 |
| 491.60 | 6.73 | 6.73 |
| 480.65 | 5.66 | 5.66 |
| 425.57 | 4.55 | 4.55 |
| 430.64 | 3.84 | 3.84 |
| 427.55 | 3.40 | 3.40 |
| 491.60 | 6.73 | 6.73 |
| 417.59 | 3.93 | 3.93 |
| 425.57 | 4.55 | 4.55 |
| 409.57 | 5.32 | 5.32 |
| 459.66 | 5.12 | 5.12 |
| 451.66 | 5.76 | 5.76 |
| 491.60 | 6.73 | 6.73 |
| 437.63 | 5.73 | 5.73 |
| 361.53 | 3.81 | 3.81 |
| 441.59 | 5.85 | 5.85 |
| 254.37 | 2.13 | 2.13 |
| 367.58 | 3.62 | 3.62 |
| 427.55 | 3.40 | 3.40 |
| 453.63 | 5.72 | 5.72 |
| 523.77 | 4.58 | 4.58 |
| 441.59 | 5.85 | 5.85 |
| 494.68 | 5.41 | 5.41 |
| 387.57 | 4.35 | 4.35 |
| 325.41 | 2.98 | 2.98 |
| 395.55 | 4.93 | 4.93 |
| 395.55 | 4.93 | 4.93 |