Basic Information
ID: ALA4360145
Type: Binding
Description: Inhibition of ICMT in human PC3 cells assessed as induction of mislocalization of endogenous Ras at 5 uM preincubated for 48 hrs followed by compound washout and subsequent compound addition measured after 72 hrs by Hoechst 33258 staining-based confocal microscopic analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4360145
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.54 | 6.01 | 6.01 |
| 423.60 | 5.71 | 5.71 |