Basic Information
ID: ALA4360248
Type: Binding
Description: Inhibition of IDH1 R132H mutant in human HCT116 cells assessed as reduction in 2-HG levels after 24 hrs by RapidFire high-throughput mass spectrometry assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4360248
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.78 | 3.67 | 3.67 |
| 385.81 | 3.03 | 3.03 |
| 355.79 | 3.02 | 3.02 |
| 395.85 | 3.90 | 3.90 |
| 339.79 | 3.32 | 3.32 |
| 324.77 | 3.37 | 3.37 |
| 353.81 | 4.23 | 4.23 |
| 373.78 | 3.16 | 3.16 |
| 413.87 | 3.81 | 3.81 |
| 354.80 | 3.63 | 3.63 |
| 425.88 | 3.81 | 3.81 |
| 354.80 | 3.63 | 3.63 |
| 338.80 | 3.93 | 3.93 |
| 354.80 | 3.63 | 3.63 |
| 462.90 | 4.00 | 4.00 |