Basic Information
ID: ALA4360250
Type: Binding
Description: Inhibition of human Myc-DDK-tagged IDH1 R132H mutant expressed in human U87MG cells assessed as reduction in 2-HG levels after 24 hrs by RapidFire high-throughput mass spectrometry assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4360250
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.78 | 3.67 | 3.67 |
| 385.81 | 3.03 | 3.03 |
| 355.79 | 3.02 | 3.02 |
| 324.77 | 3.37 | 3.37 |