ID: ALA4360333
Type: Binding
Description: Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by amplex red staining-based horseradish peroxidase/glutamate oxidase coupled assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Glutaminase kidney isoform, mitochondrial(ALA2146302)
Document: ALA4359817
Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by amplex red staining-based horseradish peroxidase/glutamate oxidase coupled assay: 1
Bioactivity
Activity Types for Assay ALA4360333
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
524.70 | 4.27 | 4.27 |
506.66 | 4.71 | 4.71 |
492.63 | 4.32 | 4.32 |
478.60 | 3.93 | 3.93 |
571.59 | 4.55 | 4.55 |
520.64 | 3.44 | 3.44 |
412.48 | 1.74 | 1.74 |
381.47 | 2.20 | 2.20 |
411.49 | 2.35 | 2.35 |
534.67 | 4.20 | 4.20 |
402.51 | 1.84 | 1.84 |
569.72 | 2.99 | 2.99 |
382.45 | 1.60 | 1.60 |
396.48 | 1.78 | 1.78 |
522.66 | 3.32 | 3.32 |
528.66 | 3.02 | 3.02 |
402.51 | 1.84 | 1.84 |
494.61 | 3.28 | 3.28 |
381.46 | 2.20 | 2.20 |
444.55 | 2.22 | 2.22 |
534.67 | 3.69 | 3.69 |
382.45 | 1.34 | 1.34 |
541.71 | 2.93 | 2.93 |
387.49 | 2.26 | 2.26 |
395.49 | 2.76 | 2.76 |
381.46 | 1.95 | 1.95 |