Basic Information
ID: ALA4360764
Type: ADME
Description: Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins in presence of NADPH by UHPLC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 1A2(ALA3356)
Document: ALA4359827
Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins in presence of NADPH by UHPLC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4360764
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.53 | 5.22 | 5.22 |
| 431.49 | 5.05 | 5.05 |
| 413.50 | 4.91 | 4.91 |
| 431.49 | 5.05 | 5.05 |
| 413.50 | 4.91 | 4.91 |